motetus: (tv / sweet zombie jesus)
[personal profile] motetus
I could write a massive 10-page essay on how low I've been feeling for the past few months due to work/masters stuff, and by stuff I mean a complete lack of progress that made me feel like an utterly worthless failure. But I think it's best if I don't - instead let's skip to what's ended all that.



This here mass of dots my postdoc gave me this week is precious to me. The black ones show that after 2 years I've finally found a way to get my stupid protein to fold correctly in its little bubble of detergent (though I suppose 2 years isn't bad after hearing about other membrane protein groups who needed 5), and the blue ones mean I have a masters thesis to write (first in vitro proof we have that this bacterial protein binds to a particular human target - could squeeze out not just a thesis from this but hopefully a decent paper). I don't even feel excited about it, I'm too busy being overwhelmed with immense, immense relief.

(but there will still be alcohol-and-cake-related celebrations at chez Motetus this weekend, and you're all invited)

Also my boss said he could extend my contract for another 18 months if I wanted. He didn't look so impressed when I said I was planning on doing a PhD elsewhere. Sorry boss, but I'd like to work in a lab where people actually talk to me. Even if it's just a hello once a day. Bloody socially inept scientists.

Date: 2011-01-28 03:45 pm (UTC)
From: [identity profile] swcajolings.livejournal.com
Congrats! And yay research! My dad has been plugging away at a chemical engineering R&D thing for the past 15-20 years so I sympathize.

Date: 2011-01-28 04:09 pm (UTC)
From: [identity profile] motetus.livejournal.com
Research isn't as easy as Hollywood would make us think. Damn it Lucius Fox, you can't syntheise an antidote for an unknown poison in 2 days. And you're not even a biologist.

Date: 2011-01-28 04:31 pm (UTC)
From: [identity profile] swcajolings.livejournal.com
Obligatory god reference.

Are you trying to tell me that the Arnold Schwarzenegger mpreg movie was a fiction??

Date: 2011-01-28 05:16 pm (UTC)
From: [identity profile] motetus.livejournal.com
Of course it was. If it was true than he would have given birth via his rectum, like they do in all good mpreg fanfic.

Date: 2011-01-28 05:44 pm (UTC)
pronker: barnabas and angelique vibing (Default)
From: [personal profile] pronker
The graph helps me visualize, thanks and it's great to hear of your triumph --- the lab, even though real quiet, sounds like it produced profound thinking.

Date: 2011-01-28 09:50 pm (UTC)
From: [identity profile] motetus.livejournal.com
Well, actually I don't really understand the graph myself, I'm just told it looks good by my post-doc. NMR is far too physicsy for me!

And if by profound thinking you mean looking at lolcats all day, then you're correct! :D

Date: 2011-01-28 06:48 pm (UTC)
From: [identity profile] temve.livejournal.com
Um... congrats! *takes marker pen and draws smiley mouth under two random blobs on chart*

Date: 2011-01-28 09:44 pm (UTC)
From: [identity profile] motetus.livejournal.com
Haha, now my next goal is to produce spectra that makes a dirty connect-the-dot picture.

Date: 2011-01-28 07:33 pm (UTC)
From: [identity profile] the-little-owl.livejournal.com
Congrats to the possibilty of writing a thesis from these dots! I just hope your protein doesn't cause harm when it binds to a human target like me.

As for the alcohol (and friendly yeast bacteria), I read the article: Sadly they produced only malt, but made no attempt at brewing beer due to too many possible, but unknown ingredients.

Date: 2011-01-28 09:57 pm (UTC)
From: [identity profile] motetus.livejournal.com
Thanks! It's going to be much easier to write a thesis when I have positive results, rather than finding ways to waffle on for thousands of words about how nothing worked.

Actually, this protein is pretty important for establishing bacterial meningitis, but you're fairly safe. For some reason it's considered unethical for me to infect humans with bacteria. Bloody unfair, if you ask me.

Date: 2011-01-28 08:38 pm (UTC)
From: [identity profile] inyadreems.livejournal.com
Yay for that! I'm glad you found a co-operative protein.

Our lab is different. We're completely ept.

Date: 2011-01-28 09:53 pm (UTC)
From: [identity profile] motetus.livejournal.com
Can I join your lab? My qualifications include may years experience of tea preparation and bringing in chocolate-based baking products (which currently goes unappreciated by my lot).

Date: 2011-02-01 07:15 pm (UTC)
From: [identity profile] inyadreems.livejournal.com
Please do! We've been trying to get more staff for months. Then I won't have to be the dogsbody any more. heh.

Date: 2011-01-29 09:08 pm (UTC)
From: [identity profile] barking-cats.livejournal.com
I'm glad that this mess of crap is of some use to you Zoe :)

Date: 2011-01-29 10:54 pm (UTC)
From: [identity profile] motetus.livejournal.com
This is not just an mess of crap, this is a mess of dispersed crap.

(honestly, I don't understand what all the dots mean. I leave that to my postdoc who just tells me it looks good)
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